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Buspirone (Prescription): An Overview

Buspirone is an anti-anxiety medication. Originally designed as an antipsychotic, the medicine was found to be unsuccessful for psychosis, although it did have helpful anxiolytic properties. Buspirone has lately gained popularity, owing to its lower side-effect profile when compared to other anxiolytic therapies. Buspirone is generally prescribed for the treatment of generalized anxiety disorder (GAD). It is an FDA-approved medication for the treatment of anxiety disorders or the temporary reduction of anxiety symptoms. Buspirone that has not been labeled is used to treat unipolar depression. 

How to take this medication?

Buspirone is available as an oral tablet. It is often taken twice a day and must be taken consistently, either with or without meals each time. Follow the instructions on your Buspirone prescription label exactly, and ask your doctor or chemist to explain any parts you don’t understand. Buspirone should be taken exactly as prescribed. Do not take more or less of it, or take it more frequently than your doctor has suggested.

Your doctor may put you on a modest dosage of buspirone and progressively raise it to once every 2 to 3 days. It may take many weeks to find a dose that works for you.

If your doctor or chemist says you may, avoid eating grapefruit or drinking grapefruit juice while taking this medicine. Grapefruit might increase the likelihood of negative effects when using this medication. For further information, see your doctor or chemist.

The dose is determined by your medical condition and reaction to therapy. To get the most out of this drug, take it on a daily basis. Use it at the same time every day to help you remember. When you start using this medicine, your anxiety symptoms (such as restlessness) may worsen before they improve. It may take up to a month or more for this drug to reach full action.

Things to Inform your Doctor Before Using This Medication:

  • Diseases of the kidneys or the liver
  • A strange or adverse reaction to buspirone or other drugs, foods, colors, or preservatives.
  • Pregnant or trying to conceive
  • Breast-feeding


It is possible to have dizziness, sleepiness, headache, nausea, uneasiness, lightheadedness, restlessness, blurred vision, weariness, and difficulty sleeping. Notify your doctor or chemist right once if any of these symptoms persist or worsen.

Remember that your doctor has recommended this medicine because the benefit to you outweighs the risk of adverse effects. Many people who use this drug have no major adverse effects.

Patients on buspirone may experience movement abnormalities such as tremors, muscular rigidity, mask-like facial expressions, jerky walking movements, or tardive dyskinesia. These symptoms may be permanent in some situations. If you see any unusual/uncontrolled movements (particularly of the face, lips, tongue, arms, or legs), contact your doctor straight away.

Seek medical treatment right away if any of the following uncommon but significant side effects occur: easy bleeding/bruising, shortness of breath, chest discomfort, or fast/irregular heartbeat.

Although a severe allergic reaction to this medication is unusual, seek quick medical assistance if one develops. A severe allergic response may include a rash, itching/swelling (particularly of the face/tongue/throat), severe dizziness, and difficulty breathing.

Take advantage of NSURx for your prescription drugs!

With the NSURx Prescription Benefit Card, you can save money on your Buspirone medications at more than 35,000 pharmacies across the United States.

You can save up to 80% on your medication by using an NSURx card. Hundreds of dollars in savings could be yours every time you fill out your prescription.

The more you shop with NSURx, the more NSUR Coins you will receive as a reward.




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