The contrast agent Gadavist also known as gadobutrol possesses magnetic characteristics. It is used in conjunction with magnetic resonance imaging (MRI) or magnetic resonance angiography (MRA) to improve visibility of blood vessels, organs, and other non-bony structures.
Gadavist is used to aid in the diagnosis of some brain and spine (central nervous system) problems, as well as blood vessels in the kidneys and the heart. Gadovist is also used in conjunction with MRI of the breast to aid in the detection of breast cancer.
Gadobutrol or Gadavist may also be used for uses other than those specified in this drug guide.
Gadavist can result in a potentially fatal situation in persons with severe renal disease. Before you get this medication, your doctor may perform a kidney function test.
Gadavist might remain in your body for months or years after you take it. It is unknown whether this may produce any health issues in persons who have normal kidneys. Inform your doctor if you have had many scans with a contrast agent and indicate the date of your most recent scan.
Gadobutrol (the active component in Gadavist) may have certain undesired side effects in addition to its necessary effects. Although not all of these adverse effects are possible, if they occur, they may necessitate medical treatment.
If any of the following side effects develop while taking gadobutrol, contact your doctor or nurse right away:
- Bleeding, blistering, burning, coldness, skin discoloration, pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site blurred vision burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings
- breathing that is laborious or labored
- dizziness, faintness, or lightheadedness after abruptly rising from a sleeping or sitting posture rapid, pounding, or irregular heartbeat or pulse
- general sensation of discomfort or sickness hives or welts, itching or skin rash loss of consciousness
- Seizures sweating tightness in the chest unusual weariness or weakness paleness of the skin redness of the face, neck, arms, and occasionally the upper chest
- Bluish color of the fingernails, lips, skin, palms, or nail beds
- burning sensation
- burning, dry, or itching eyes
- chest pain
- decreased or uncontrolled urination
- deep bone pain
- difficulty with swallowing
- discharge or excessive tearing
- increased sweating
- lack or loss of strength
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
- muscle stiffness or weakness
- no blood pressure or pulse
- no breathing
- noisy breathing
- numbness, tingling, pain, or weakness in the hands or feet
- paralysis or severe weakness of the legs
- redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
- skin rash, swelling, hardness, tightness, burning, itching, or red or dark patches
- slow or irregular breathing
- stiff joints or trouble moving
- stopping of the heart
- swelling of the mouth or throat
- uncontrolled bowel movements
- uncontrolled movements of the body
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