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Atorvastatin (Lipitor®): What You Need to Know

If diet and exercise aren’t enough to lower your cholesterol, you may need to take medication.

The first line of defense against high cholesterol is a healthy lifestyle. However, food and exercise aren’t always enough. It’s possible that you’ll need to take cholesterol meds as well.

A single pill or a combination of cholesterol drugs may be recommended by your doctor. Atorvastatin (Lipitor) is one of them.

What is Atorvastatin (Lipitor) and what does it do?

HMG CoA reductase inhibitors, or “statins,” are a class of medications used to treat cholesterol that include Atorvastatin (Lipitor).

Atorvastatin (Lipitor) is used to lower “bad” cholesterol (low-density lipoprotein, or LDL), raise “good” cholesterol (high-density lipoprotein, or HDL), and lower triglycerides (a type of fat in the blood).

What doses of Atorvastatin (Lipitor) are available?

There are many strengths of Atorvastatin (Lipitor) that your doctor can recommend, from 10 mg to 80 mg, and potentially higher. The following factors will affect the dosage, drug form, and frequency with which you take the drug:

  • Your age
  • The illness that is being treated
  • The severity of your issue
  • Additional medical issues you’re dealing with
  • How the first dose affects you

Dosage for Adults (ages 18–64)

  • The typical starting dosage is 10-20 mg and is taken daily.
  • Typical daily dosage ranges from 10 to 80 mg.
  • Note: The recommended daily dose for treating homozygous familial hypercholesterolemia is 10–80 mg administered once daily.

Dosage for Children (ages 10–17)

Atorvastatin (Lipitor) is exclusively given to children with heterozygous familial hypercholesterolemia to lower their cholesterol.

  • The typical starting dosage is 10 mg and is taken daily.
  • The maximum daily dose is usually 20 mg.

Dosage for Children (ages 0–9)

Atorvastatin (Lipitor) has not been studied in children under the age of ten. It’s not suitable for this age range.

Dosage for Senior (ages 65 years and older)

When people get older, their kidneys may be less efficient. This can slow down your body’s ability to digest medications. Because of this, you’re able to take in more medication and have it stay in your system for longer. There is a greater chance of side effects as a result.

Dosage adjustments or a new plan may be recommended by your physician. This can help keep your body’s concentrations of the medicine from rising dangerously high.

What side effects are common with taking Atorvastatin (Lipitor)?

If you have symptoms of an allergic response to Atorvastatin (Lipitor), such as hives, difficulty breathing, or swelling of your face, lips, tongue, or neck, seek medical attention right away.

In rare cases, Atorvastatin (Lipitor) can cause skeletal muscle tissue damage, which can lead to kidney failure. In the event that you’re experiencing persistent or unexplained discomfort, tenderness, or weakening in your muscles, see your doctor right away, especially if you also have a fever, unusual tiredness, or dark urine.

If you notice any of the following symptoms from Atorvastatin (Lipitor), consult your doctor.

  • Your hips, shoulders, neck, and back muscles are weak.
  • Difficulty extending your arms and struggling to stand or climb;
  • Upper stomach pain, weakness, exhaustion, a lack of appetite, dark urine, and jaundice (a yellowing of the skin or eyes) are all symptoms of liver dysfunction.
  • Swelling of the feet or ankles, fatigue, or shortness of breath are all symptoms of kidney disease.

Common Atorvastatin (Lipitor) side effects may include:

  • Joint pain;
  • Stuffy nose, sore throat;
  • Diarrhea; or
  • Pain in your arms or legs.

Does Atorvastatin (Lipitor) interact with other medications?

Other medications, vitamins, or herbs you may be taking may interact with Atorvastatin (Lipitor) oral tablets. When a chemical changes the way a drug functions, this is known as an interaction. This can be hazardous or decrease the drug’s effectiveness.

To avoid drug interactions, your doctor will closely monitor all of your medications. Make sure your doctor is aware of any drugs, supplements, or herbs you’re using. Consult your doctor or pharmacist to learn how this medication may interact with other medications you’re taking.

The following are some examples of medicines that may interact with Atorvastatin (Lipitor):


When you take Atorvastatin (Lipitor) with certain antibiotics, you run the risk of muscular issues. The following are some examples of these drugs:

  • Clarithromycin
  • Erythromycin

Fungal Drugs

When you take Atorvastatin (Lipitor) with some medications that treat fungal infections, Atorvastatin (Lipitor) can build up in your system. This puts you at a higher risk of muscular breakdown. If you must take these medications together, your doctor may reduce your Atorvastatin (Lipitor) dosage. The following are some examples of these drugs:

  • Itraconazole
  • Ketoconazole

Other Cholesterol-Lowering Drugs

When you combine Atorvastatin (Lipitor) with other cholesterol-lowering medications, you run the risk of developing muscular issues. Your doctor may advise you to take these medications in different amounts or to avoid taking them at the same time. The following are some examples of these drugs:

  • Gemfibrozil
  • Medications that contain fibrate
  • Niacin


When you take Rifampin with Atorvastatin (Lipitor), the amount of Atorvastatin (Lipitor) in your body may decrease. As a result, Atorvastatin (Lipitor) may not be as effective.

HIV Drugs

When you use Atorvastatin (Lipitor) with some HIV medicines, Atorvastatin (Lipitor) can build up in your body. This puts you at a higher risk of muscular breakdown. If you must take these medications together, your doctor may reduce your Atorvastatin (Lipitor) dosage. Protease inhibitors, for instance, include:


When Digoxin is combined with Atorvastatin (Lipitor), the amount of Digoxin in your blood can rise to harmful levels. When taking these drugs together, your doctor will monitor your blood levels and adjust your prescription doses as needed.

Oral Birth Control Pills

When you use Atorvastatin (Lipitor) with oral birth control pills, your blood levels of oral contraceptive hormones may rise.


Colchicine combined with Atorvastatin (Lipitor) increases the risk of muscle breakdown.


When you take Cyclosporine with Atorvastatin (Lipitor), your risk of muscle breakdown increases. Your doctor should avoid thighs combination.

Who should NOT take Atorvastatin (Lipitor)?

People with kidney problems

If you have kidney problems, you’re more likely to experience muscle breakdown while taking Atorvastatin (Lipitor). If you have muscle difficulties, your doctor may want to keep an eye on you more closely.

If you have liver disease, you should avoid using this medication since it can cause your liver test results to worsen. This could indicate that you have liver disease. If you have liver problems, consult your doctor to ensure that this medication is appropriate for you.


For diabetics, Atorvastatin (Lipitor) may cause blood sugar levels to rise. If this happens, your diabetes medications may need to be adjusted, and you may need to monitor your blood sugar levels more frequently than normal while taking this treatment.

Those pregnant or breastfeeding

When it comes to pregnant ladies, Atorvastatin (Lipitor) should never be utilized. The drug’s safety in pregnant women is unknown, and it appears to have little benefit during pregnancy.If you become pregnant while using this medication, contact your doctor right away.

Atorvastatin (Lipitor) should not be taken by women who are breastfeeding. If you’re a breastfeeding mother, talk to your doctor about which medications might be appropriate for you.

When using Atorvastatin (Lipitor), those over the age of 65 are at an increased risk of muscular breakdown (rhabdomyolysis).


Atorvastatin (Lipitor) has not been studied in children under the age of ten, and it should not be taken in children under the age of ten. This medication has been proven to be safe and effective in children aged 10 to 17.

Are there any special precautions I should follow before taking Atorvastatin (Lipitor)?

This medication comes with a number of warnings.

Allergy Warning

An allergic reaction to Atorvastatin (Lipitor) can be life-threatening. The following are possible signs and symptoms:

  • A swollen or inflamed face, mouth, or throat
  • Trouble breathing
  • Trouble swallowing

If you’ve ever had an adverse reaction to this medication, don’t take it again. It could be fatal if you take it again (cause death).

Food Interactions Warning

When using Atorvastatin (Lipitor), avoid drinking a lot of grapefruit juice. Grapefruit juice consumption can cause an increase in Atorvastatin (Lipitor) levels in the blood, increasing the risk of muscle breakdown. Consult your doctor to determine how much grapefruit juice is safe for you to consume.

Alcohol Interaction Warning

The usage of alcoholic beverages increases your risk of Atorvastatin (Lipitor)-induced liver damage. If you consume more than two alcoholic beverages every day, consult your doctor.

What drugs are similar to Atorvastatin (Lipitor)?

There are various medications that can be used to treat your condition. Some could be more appropriate for you than others. This include:

Does Atorvastatin (Lipitor) have a generic form?

Atorvastatin is the generic form of Lipitor. A generic drug is a near-identical replica of the active ingredient in a brand-name drug. The generic medicine is thought to be just as safe and effective as the brand-name version.

What is the price of Atorvastatin (Lipitor) without insurance?

With a coupon, the cost of Atorvastatin (Lipitor) without insurance starts at $9.23 for 30 tablets of 40mg.

The cost of Atorvastatin (Lipitor) and the brand-name drug Lipitor varies depending on the pharmacy and location. It’s crucial to remember that generic medication is often far less expensive than brand-name medication and is frequently prescribed as a means to save money on prescriptions.

How can I save money on Atorvastatin (Lipitor) ?

With the NSURx Prescription Benefit Card, you may save money on Atorvastatin (Lipitor) at over 35,000 pharmacies across the United States.

You can save up to 80% on Atorvastatin (Lipitor) when you use an NSURx card. This might save you THOUSANDS of dollars each time you fill your script.

The more you shop with NSURx, the more NSUR Coin you will receive as a reward. You can then use those coins to make purchases on our online store.

Rheanne Blest Razo

Rheanne Blest Razo

Rheanne Blest is an experienced content writer, virtual assistant and a fellow crypto enthusiast. In the past, she has managed relationships with enterprise clients like BMW, digital projects for start-up companies like NSUR Coin, and the day-to-day operations of an automotive custom house and lighting company.
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